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Severe flu can cause 'taste Bud cells' to grow in the lungs

2019-4-22 16:21| 发布者: 左二爷| 查看: 288| 评论: 0|来自: 成都桑拿网www.scshuashua114.com

摘要: While most of us get rid of the flu in a week or two, in more extreme cases, the virus actually reconstructs the lungs. Now, researchers at the University of Pennsylvania have discovered an important ...
While most of us get rid of the flu in a week or two, in more extreme cases, the virus actually reconstructs the lungs. Now, researchers at the University of Pennsylvania have discovered an important part of this recombination that has not been noticed until now -- "taste Bud cells" seem to grow in the lungs after severe flu cases.
In the new study, the team carried out a more in-depth study of inflammation in mice exposed to H1N1 flu. This reaction is usually part of the immune system type 2 reaction, but the flu itself only triggers a type 1 immune response. One piece of the puzzle is missing -- this inflammation usually requires cluster cells. These cells are almost identical to taste buds, and they have been found to be responsible for intestinal inflammation.

The team found that the clusters of cells were located in the airway and alveoli, a tiny balloon structure that allows gas to be exchanged with blood. The results showed that genealogical epithelium progenitor cells lead to cluster cells, as well as other cells that destroy lung structure after infection.
Next, the team tested what the taste buds cells were actually doing. They used bitter compounds to activate them and found that their number increased, followed by acute inflammation. When they compared the results to uninfected lungs, there were no cluster cells and no inflammatory response.
The researchers say the cells may be linked to diseases such as allergies and asthma. As a result, they may become new targets for treatment of these diseases. Next, the team plans to investigate whether the same thing happened to the lungs.

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